Date of Award

2010

Document Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

First Advisor

Goktepe, Ipek

Abstract

Since studies involving the activities of P. americana extracts on various cancer cell lines are limited, the major objectives of this study were to: 1) evaluate the antiproliferative activity of three extracts from P. americana against human breast (MCF-7) and colon cancer (HCT-116) cells in vitro and 2) investigate the changes at the protein and gene levels after exposing the HCT-116 cells to P. americana extracts in vitro.

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