Cellulose-based Biorenewable Hydrogels: Manuka Honey and Sustainable Polymers for optimized Wound healing

Cellulose-based Biorenewable Hydrogels: Manuka Honey and Sustainable Polymers for optimized Wound healing

Hoda Motaghed, Joint School of Nanoscience and Nanoengineering, Joint School of Nanoscience and Nanoengineering, North Carolina Agricultural and Technical State University

Description

This systematic study investigates the development of biorenewable, cellulose-based wound dressings by incorporating antibacterial agents into advanced polymeric hydrogels. To enhance their therapeutic properties, Manuka honey is blended with biodegradable polymers, including chitosan, gelatin, bacterial cellulose, and PCL. Various fabrication techniques— such as electrospinning, hydrogel formation, and 3D printing —are employed to optimize the hydrogel composites' porosity, mechanical strength, and biodegradability. The controlled release of Manuka honey is designed to ensure sustained antimicrobial activity while promoting cell adhesion and tissue regeneration. Hence, this study addresses key challenges like antibiotic resistance and the demand for customizable, cost-effective wound care solutions; this research paves the way for improved wound healing strategies