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Description

Molecular photoswitches allow external control over molecular structure and reactivity using light. We proposed creating a photoswitching directing template for opportunities in regio-divergent site-selectivity and unique geometrical approaches to remote C-H bonds. A photoswitchable "C-shaped" directing template will be designed from the excited “T-shaped” conformers of azo heteroarenes to investigate functionalization by switching between trans and cis conformers under light. This work will share our initial synthesis of key intermediates and studies of their photoswitchability. We end by outlining our future work for realizing goals in remote C-H functionalization with projected screening conditions for optimal functionalization.

Publication Date

4-1-2025

Keywords

molecular photoswitches, light-responsive molecules, regioselectivity, C-H functionalization, photoswitchable templates, azo heteroarenes, trans-cis isomerization, remote functionalization, site-selective chemistry, photochemistry, conformational switching, synthetic intermediates, photochemical control, directing groups, molecular design

“Photoswitchable” Directing Template for Remote C-H Bond Functionalization

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