Detection of Alu Insertion Polymorphism in Human

Student Classification

Junior

Faculty Mentor

Mulumebet Worku, Ph.D.

Department

Department of Animal Sciences

Document Type

Poster

Publication Date

Spring 2019

Disciplines

Animal Sciences | Molecular Genetics

Abstract

The Alu insertions polymorphism are short stretches of DNA, which are the most abundant transposable polymorphisms that may reach over one million copies dispersed throughout the human genome. The objective of this project is to detect the Alu insertion in human genome using polymerase chain reaction (PCR). The DNA samples were extracted from the saliva of four humans. The PCR then was used to amplify the Alu insertions with the Biorad kit (PV92 PCR Informatics Kit). The PCR product was analyzed with gel electrophoresis. The results show the three types of Alu insertions.

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