The Effects of a 16-Week Exercising Program on Inflammatory Markers in Human Milk

Student Classification


Faculty Mentor

Heather Colleran, Ph.D.


Department of Family and Consumer Sciences; Food and Nutritional Sciences

Document Type


Publication Date

Fall 2018


Food Science | Nutrition


Exercising during pregnancy is prominent for lowering systemic inflammation. Information on the effects that exercising has on human milk inflammatory markers is limited. Thus, it is critical to closely monitor both the control group and the exercise group post-partum to analyze the pro- and anti-inflammatory signals in human milk. A consistent exercising program has been found to reduce the proinflammatory markers within human milk, but specifically within colostrum. An exercising program has also been found to increase the number of fractalkine concentrations within human milk, which may foster neurodevelopment and neuroprotection in newborns. Post-baseline measurements randomization into either the exercise group or control group. The exercise protocol included a 60-minute exercise, at a maximum heart rate intensity of 65-80%, three days per week. The exercise intervention included both aerobic and strengthening training. The control group was instructed to avoid structured exercise and both groups were instructed normal dietary intake. Both groups were also given multivitamin supplements that contained 100% RDA, including 400 IU of vitamin D and 400 mcg of folic acid. mature human milk proinflammatory and anti-inflammatory cytokines (fractalkine, interleukin [IL]–1β, IL-6, IL-8, IL-10, interferon [IFN]–γ, and tumor necrosis factor [TNF]–α) will be measured using Luminex xMAP technology.

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